Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068147 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4EHPGDGFER | |
| SCHEMBL7070861 | 0.77 | ALDH1A1 (0.45) | ALDH1A1GAAKDM4EHPGDGFER | |
| SCHEMBL10106495 | 0.77 | GAA (0.45) | ALDH1A1GAAKDM4EHPGDGFER | |
| SCHEMBL11887839 | 0.76 | TDP1 (0.71) | ALDH1A1KDM4EHPGDGFERTDP1 | |
| SCHEMBL7067443 | 0.75 | ALDH1A1 (0.45) | ALDH1A1GAAKDM4EHPGDGFER | |
| Vp-14637 SCHEMBL16743389 | 0.68 | GAA (0.45) | ALDH1A1GAAKDM4EHPGDGFER | |
| SCHEMBL642652 | 0.68 | GAA (0.43) | ALDH1A1GAAKDM4EHPGDGFER | |
| SCHEMBL13779303 | 0.68 | TDP1 (1.00) | ALDH1A1GAAKDM4EHPGDGFER | |
| SCHEMBL642282 | 0.68 | GAA (0.42) | ALDH1A1GAAKDM4EHPGDGFER | |
| SCHEMBL644706 | 0.68 | GAA (0.42) | ALDH1A1GAAKDM4EHPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | NITZ THEODORE J (US) | 2003-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | TTPA, HAVCR2, PML | ALDH1A1 3369/4885GAA 1534/4885KDM4E 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.