Vp-14637

Vp-14637

SCHEMBL16743389

Cc1nnnn1/N=C/c1ccc(O)c(C(c2ccc(O)cc2)c2cc(/C=N/n3nnnc3C)ccc2O)c1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
KDM4E B2RXH2 6/20 0.45
HPGD P15428 4/20 0.45
GFER P55789 1/20 0.45
ALDH1A1 P00352 5/20 0.43
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.35
PABPC1 P11940 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
AMY1A P0DUB6 2/20 0.33
GUSB P08236 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vp-14637 SCHEMBL29351615 1.00 GAA (0.45) GAAKDM4EHPGDGFERALDH1A1
Vp-14637 SCHEMBL20741449 1.00 GAA (0.45) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL7070861 0.91 ALDH1A1 (0.45) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL10106495 0.91 GAA (0.45) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL22788662 0.89 KDM4E (0.49) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL7067443 0.89 ALDH1A1 (0.45) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL7068147 0.88 ALDH1A1 (0.41) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL21117062 0.86 GAA (0.38) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL642652 0.86 GAA (0.43) GAAKDM4EHPGDGFERALDH1A1
SCHEMBL6215111 0.86 GAA (0.40) GAAKDM4EHPGDGFERALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066065-A1 PLATELET DERIVATIVES FOR TREATING COAGULOPATHY CELLPHIRE, INC. (US) 2024-02-29 US claimed
US-20220279777-A1 FREEZE-DRIED PLATELET DERIVATIVE COMPOSITIONS FOR TREATING ANTICOAGULANT-INDUCED COAGULOPATHY CELLPHIRE INC. (US) 2022-09-08 US claimed
WO-2022178191-A1 FREEZE-DRIED PLATELET DERIVATIVE COMPOSITIONS FOR TREATING ANTICOAGULANT-INDUCED COAGULOPATHY CELLPHIRE, INC. (US) 2022-08-25 WO claimed
EP-4013432-A1 THROMBOSOMES AS AN ANTICOAGULANT REVERSAL AGENT Cellphire Inc. (US) 2022-06-22 EP claimed
US-12454520-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2025-10-28 US disclosed
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-07-03 US disclosed
US-20250177450-A1 METHODS FOR ADMINISTERING FREEZE-DRIED PLATELET DERIVATIVE COMPOSITIONS TO SUBJECTS TREATED WITH A FACTOR XI INHIBITOR CELLPHIRE, INC. (US) 2025-06-05 US disclosed
US-20250073271-A1 METHODS OF ADMINISTERING PLATELET DERIVATIVE COMPOSITIONS TO REDUCE BLEEDING IN SUBJECTS REFRACTORY TO PLATELET TRANSFUSION CELLPHIRE, INC. (US) 2025-03-06 US disclosed
US-20250064856-A1 METHODS FOR ADMINISTERING PLATELET DERIVATIVE COMPOSITIONS TO SUBJECTS AFFLICTED WITH HERMANSKY PUDLAK SYNDROME OR BERNARD SOULIER SYNDROME CELLPHIRE, INC. (US) 2025-02-27 US disclosed
WO-2024229305-A1 PLATELET DERIVATIVE COMPOSITIONS FOR USE IN CONTROLLING BLEEDING IN A SUBJECT CELLPHIRE, INC. (US) 2024-11-07 WO disclosed
US-20240307453-A1 METHODS FOR CONTROLLING BLEEDING IN A SUBJECT AFFLICTED WITH HERMANSKY PUDLAK SYNDROME USING PLATELET DERIVATIVE COMPOSITIONS CELLPHIRE, INC. (US) 2024-09-19 US disclosed
WO-2024192173-A1 HLA-CHARACTERIZED PLATELET DERIVATIVE COMPOSITIONS, AND METHODS OF MAKING, SELECTING AND USING SUCH COMPOSITIONS CELLPHIRE, INC. (US) 2024-09-19 WO disclosed
US-20170100385-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) 2017-04-13 US disclosed
US-20170100385-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) 2017-04-13 US disclosed
US-9504672-B2 Compositions and methods for treating or preventing pneumovirus infection and associated diseases MICRODOSE THERAPEUTX, INC. (US) 2016-11-29 US disclosed
US-9504672-B2 Compositions and methods for treating or preventing pneumovirus infection and associated diseases MICRODOSE THERAPEUTX, INC. (US) 2016-11-29 US disclosed
US-20150209328-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES MICRODOSE THERAPEUTX, INC. (US) 2015-07-30 US disclosed
US-20150209328-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES MICRODOSE THERAPEUTX, INC. (US) 2015-07-30 US disclosed
US-9040569-B2 Compositions and methods for treating or preventing pneumovirus infection and associated diseases MICRODOSE THERAPEUTX (US) 2015-05-26 US disclosed
US-9040569-B2 Compositions and methods for treating or preventing pneumovirus infection and associated diseases MICRODOSE THERAPEUTX (US) 2015-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150209328-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES MDN1, PRTN3, MBTD1 GAA 2624/4885KDM4E 4771/4885HPGD 2125/4885
US-12454520-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 GAA 269/4885KDM4E 935/4885HPGD 3521/4885
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 GAA 269/4885KDM4E 935/4885HPGD 3521/4885
US-20170100385-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES DDOST, DHX30, DDX5 GAA 123/4885KDM4E 4515/4885HPGD 2249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.