SCHEMBL7071185

SCHEMBL7071185

CCC1(COC(=O)C(C)(C)C)COC(=O)C(CC)(CC)N1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 17/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PRKCE Q02156 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071689 0.84 SMN1; SMN2 (0.39) PRKCASMN1; SMN2PRKCE
SCHEMBL7068994 0.79
SCHEMBL7070377 0.76 KDM4E (0.31)
SCHEMBL7072491 0.70 SMN1; SMN2 (0.41) PRKCASMN1; SMN2PRKCE
SCHEMBL4953813 0.67 PRKCA (0.38) PRKCASMN1; SMN2PRKCE
SCHEMBL4952249 0.67 SMN1; SMN2 (0.38) PRKCASMN1; SMN2PRKCE
SCHEMBL4952252 0.67 SMN1; SMN2 (0.38) PRKCASMN1; SMN2PRKCE
SCHEMBL4953817 0.67 PRKCA (0.38) PRKCASMN1; SMN2PRKCE
SCHEMBL7071097 0.66 KDM4E (0.33)
SCHEMBL12059177 0.65 PRKCA (0.39) PRKCASMN1; SMN2PRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664353-B2 Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-16 US disclosed
US-20030125494-A1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes NESVADBA PETER (CH) 2003-07-03 US disclosed
US-6479608-B1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-12 US disclosed