Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 17/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072491 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2PRKCAPRKCEPRKCD | |
| SCHEMBL7071185 | 0.84 | PRKCA (0.36) | SMN1; SMN2PRKCAPRKCE | |
| SCHEMBL7067960 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL4953813 | 0.69 | PRKCA (0.38) | SMN1; SMN2PRKCAPRKCEPRKCD | |
| SCHEMBL4953817 | 0.69 | PRKCA (0.38) | SMN1; SMN2PRKCAPRKCEPRKCD | |
| SCHEMBL7071097 | 0.69 | KDM4E (0.33) | — | |
| SCHEMBL12059177 | 0.68 | PRKCA (0.39) | SMN1; SMN2PRKCAPRKCEPRKCD | |
| SCHEMBL4954531 | 0.67 | PRKCA (0.40) | SMN1; SMN2PRKCAPRKCEPRKCD | |
| SCHEMBL13993294 | 0.67 | SMN1; SMN2 (0.40) | SMN1; SMN2PRKCAPRKCEPRKCD | |
| SCHEMBL4954525 | 0.67 | PRKCA (0.40) | SMN1; SMN2PRKCAPRKCEPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664353-B2 | Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-12-16 | — | — | US | disclosed |
| US-20030125494-A1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6479608-B1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-12 | — | — | US | disclosed |