SCHEMBL7072491

SCHEMBL7072491

CC1(COC(=O)C(C)(C)C)COC(=O)C(C)(C)N1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.41
PRKCA P17252 17/20 0.38
PRKCD Q05655 2/20 0.34
PRKCE Q02156 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071689 0.85 SMN1; SMN2 (0.39) SMN1; SMN2PRKCAPRKCDPRKCE
SCHEMBL77995 0.77 CA1 (0.41) PRKCD
SCHEMBL6549621 0.76 PRKCA (0.52) PRKCAPRKCDPRKCE
SCHEMBL5323355 0.74 ALDH1A1 (0.36)
SCHEMBL4954525 0.72 PRKCA (0.40) SMN1; SMN2PRKCAPRKCDPRKCE
SCHEMBL4954531 0.72 PRKCA (0.40) SMN1; SMN2PRKCAPRKCDPRKCE
SCHEMBL7071185 0.70 PRKCA (0.36) SMN1; SMN2PRKCAPRKCE
SCHEMBL13993294 0.70 SMN1; SMN2 (0.40) SMN1; SMN2PRKCAPRKCDPRKCE
SCHEMBL13811598 0.68 SMN1; SMN2 (0.41) SMN1; SMN2PRKCAPRKCDPRKCE
SCHEMBL13811744 0.67 EPHX1 (0.40) SMN1; SMN2PRKCAPRKCDPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664353-B2 Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-16 US disclosed
US-20030125494-A1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes NESVADBA PETER (CH) 2003-07-03 US disclosed
US-6479608-B1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-12 US disclosed