Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720485 | 0.93 | HSD17B10 (0.50) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL31473042 | 0.93 | HSD17B10 (0.56) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL254345 | 0.93 | HSD17B10 (0.56) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| Methane SCHEMBL9652566 | 0.85 | KDM4E (0.51) | HSD17B10MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL28401167 | 0.83 | CYP17A1 (0.47) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL4626521 | 0.80 | HSD17B10 (0.55) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL2114613 | 0.80 | KLKB1 (0.50) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| Bicarbonate SCHEMBL7184926 | 0.79 | LMNA (0.56) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| Bicarbonate SCHEMBL11212986 | 0.79 | LMNA (0.56) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL351082 | 0.79 | POLB (0.55) | HSD17B10MEN1KMT2ACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738745-B1 | Polyimide precursor, polyimide and their use | HITACHI CHEMICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-0738745-A1 | Polyimide precursor, polyimide and their use | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |