Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071466 | 0.86 | MEN1 (0.33) | MEN1KMT2ATDP1TK1 | |
| SCHEMBL674037 | 0.83 | GRIN1 (0.42) | MEN1KMT2ATDP1 | |
| SCHEMBL675171 | 0.82 | KMT2A (0.35) | MEN1KMT2ATDP1 | |
| SCHEMBL6087585 | 0.82 | KMT2A (0.35) | MEN1KMT2ATDP1 | |
| SCHEMBL6088384 | 0.81 | GRIN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL7068410 | 0.81 | GRIN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL6086562 | 0.81 | MTOR (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL7073641 | 0.80 | — | — | |
| SCHEMBL7070503 | 0.80 | TK1 (0.30) | TK1 | |
| SCHEMBL12752190 | 0.80 | KMT2A (0.39) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827498-B1 | NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | SAMJIN PHARM CO LTD (KR) | 2003-06-18 | — | — | EP | disclosed |