Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222447 | 0.82 | G6PD (0.50) | G6PDCASP7CASP6ALOX15MMP2 | |
| SCHEMBL31634613 | 0.76 | ALDH1A1 (0.58) | G6PDCASP7CASP6ALOX15MMP2 | |
| SCHEMBL465737 | 0.76 | ALDH1A1 (0.58) | G6PDCASP7CASP6ALOX15MMP2 | |
| Methoxymethane SCHEMBL5903652 | 0.76 | G6PD (0.63) | G6PDCASP7CASP6ALOX15MMP2 | |
| SCHEMBL9928673 | 0.73 | TSHR (0.52) | ALDH1A1HSD17B10TSHRMAPK1F2 | |
| SCHEMBL13816768 | 0.72 | ALDH1A1 (0.62) | G6PDCASP7CASP6ALOX15ALDH1A1 | |
| SCHEMBL526919 | 0.72 | G6PD (0.74) | G6PDCASP7CASP6ALOX15MMP2 | |
| SCHEMBL25083557 | 0.72 | ALDH1A1 (0.45) | ALOX15ALDH1A1HSD17B10TSHRMYC | |
| SCHEMBL11080330 | 0.70 | GRM6 (0.40) | G6PDCASP7CASP6ALOX15MMP2 | |
| SCHEMBL28281319 | 0.70 | G6PD (0.71) | G6PDCASP7CASP6ALOX15MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003052053-A2 | NUCLEOSIDE LIBRARIES AND COMPOUNDS BY MCC COMBINATORIAL STRATEGIES ON SOLID SUPPORT | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |