SCHEMBL707221

SCHEMBL707221

C[Si](C)(CC[Si](C)(C)Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 4/20 0.39
TSHR P16473 1/20 0.39
KCNA3 P22001 1/20 0.39
HTR1B P28222 2/20 0.35
KCNH2 Q12809 1/20 0.35
LMNA P02545 1/20 0.35
HTR1D P28221 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RECQL P46063 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13089513 0.93 CA4 (0.37) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL706868 0.91 KCNA3 (0.41) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL703963 0.91 KCNA3 (0.41) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL710740 0.85 CA4 (0.42) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL6987433 0.85 LTA4H (0.46) LTA4HTSHRKCNA3KCNH2LMNA
SCHEMBL8961710 0.83 LTA4H (0.46) LTA4HKCNA3KCNH2LMNAALDH1A1
SCHEMBL3913247 0.83 KCNA3 (0.35) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL3923699 0.83 KCNA3 (0.40) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL19816761 0.83 LTA4H (0.40) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL23532445 0.82 SMN1; SMN2 (0.40) LTA4HTSHRKCNA3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND JSR CORPORATION (JP) 2010-10-14 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND GMNN, GEMIN5, SEPTIN7 CA4 147/4885LTA4H 2152/4885TSHR 4191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.