Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560505 | 0.92 | KCNA3 (0.34) | KCNA3LTA4HHTR1BL3MBTL1DRD2 | |
| SCHEMBL706868 | 0.88 | KCNA3 (0.41) | KCNA3LTA4HHTR1BL3MBTL1DRD2 | |
| SCHEMBL703963 | 0.88 | KCNA3 (0.41) | KCNA3LTA4HHTR1BL3MBTL1DRD2 | |
| SCHEMBL3923262 | 0.85 | KCNA3 (0.40) | KCNA3LTA4HHTR1BL3MBTL1DRD2 | |
| SCHEMBL707221 | 0.83 | CA4 (0.42) | KCNA3LTA4HHTR1BL3MBTL1KCNH2 | |
| SCHEMBL6987433 | 0.82 | LTA4H (0.46) | KCNA3LTA4HDRD2DRD3KCNH2 | |
| SCHEMBL8961710 | 0.81 | LTA4H (0.46) | KCNA3LTA4HDRD2DRD3KCNH2 | |
| SCHEMBL3913247 | 0.81 | KCNA3 (0.35) | KCNA3LTA4HHTR1BL3MBTL1KCNH2 | |
| SCHEMBL3923803 | 0.80 | KCNA3 (0.43) | KCNA3LTA4HHTR1BL3MBTL1DRD2 | |
| SCHEMBL3914716 | 0.79 | CA4 (0.39) | KCNA3LTA4HHTR1BKCNH2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954701-B1 | PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| EP-1249454-A1 | Preparation of unsaturated organo-silicon compounds | Wacker-Chemie GmbH (DE) | 2002-10-16 | — | — | EP | disclosed |