SCHEMBL7072785

SCHEMBL7072785

CN(C)S(=O)(=O)NCC1CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.38
ALDH1A1 P00352 4/20 0.37
THRB P10828 1/20 0.36
LMNA P02545 2/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30716703 0.81 KDM4E (0.43) KDM4EALDH1A1THRBLMNAMAPT
SCHEMBL6935344 0.81 KDM4E (0.43) KDM4EALDH1A1THRBLMNAMAPT
SCHEMBL6355414 0.80 KDM4E (0.42) KDM4EALDH1A1THRBLMNAMAPT
SCHEMBL3649759 0.78 KDM4E (0.40) KDM4EALDH1A1THRBLMNAMAPT
SCHEMBL3645416 0.78 KDM4E (0.40) KDM4EALDH1A1THRBLMNAMAPT
SCHEMBL6351927 0.76 KDM4E (0.45) KDM4EALDH1A1LMNAMAPTPKM
SCHEMBL13595432 0.75 KDM4E (0.36) KDM4EALDH1A1LMNAMAPTPKM
SCHEMBL775569 0.74 KDM4E (0.35) KDM4EALDH1A1LMNAMAPTPKM
SCHEMBL8077229 0.74 KDM4E (0.42) KDM4EALDH1A1LMNATDP1MEN1
SCHEMBL2632934 0.72 KDM4E (0.34) KDM4EALDH1A1PKMTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157058-B1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS SUMITOMO BAKELITE CO (JP) 2003-06-25 EP disclosed
US-6420503-B1 POLYCARBONS/OTHER/ SUMITOMO BAKELITE CO. LTD. (JP) 2002-07-16 US disclosed
EP-1157058-A1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS The B.F. Goodrich Company (US) 2001-11-28 EP disclosed
US-6235849-B1 INCLUDE COPOLYMERS WITH ONE OR MORE COMONOMERS SUCH AS NORBORNENE, ETHYLENE, AN ACRYLATE OR SULFUR DIOXIDE OR CARBON MONOXIDE; ALSO RING-OPENING METATHESIS POLYMERIZATION; GROUP VIII METAL COMPOUND CATALYST THE B. F. GOODRICH COMPANY 2001-05-22 US disclosed
WO-2000046267-A1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS THE B.F. GOODRICH COMPANY (US) 2000-08-10 WO disclosed