Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071186 | 0.89 | ESR1 (0.31) | — | |
| SCHEMBL7073667 | 0.79 | DYRK1A (0.34) | — | |
| SCHEMBL6797675 | 0.69 | SHBG (0.44) | SHBGOPRM1OPRK1DRD2DRD3 | |
| SCHEMBL7072995 | 0.65 | SHBG (0.31) | SHBG | |
| SCHEMBL6801524 | 0.60 | OPRM1 (0.37) | SHBGOPRM1OPRK1 | |
| SCHEMBL7073703 | 0.60 | DYRK1A (0.34) | — | |
| SCHEMBL806085 | 0.58 | SHBG (0.47) | SHBGOPRM1OPRK1 | |
| SCHEMBL14489029 | 0.56 | SHBG (0.51) | SHBGOPRM1OPRK1DRD2DRD3 | |
| SCHEMBL13303203 | 0.55 | SHBG (0.37) | SHBGDRD2DRD3 | |
| SCHEMBL13303151 | 0.54 | DYRK1A (0.44) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339662-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046134-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2002-06-13 | — | — | WO | disclosed |