SCHEMBL7071186

SCHEMBL7071186

CCC1c2ccc(O)cc2C(C)C12C=c1ccc(O)cc1=C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7072786 0.89 SHBG (0.34)
SCHEMBL7073667 0.81 DYRK1A (0.34)
SCHEMBL6801524 0.68 OPRM1 (0.37) ESR1ESR2
SCHEMBL7073703 0.62 DYRK1A (0.34)
SCHEMBL4412333 0.57 ESR1 (0.40) ESR1ESR2
SCHEMBL5951499 0.56 ESR1 (0.60) ESR1ESR2
SCHEMBL6798568 0.56 OPRM1 (0.39) ESR1ESR2
SCHEMBL8590825 0.55 DYRK1A (0.43) ESR1
SCHEMBL16093289 0.55 SHBG (0.41) ESR1ESR2
SCHEMBL23072173 0.54 HTR2B (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339662-A1 NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III KARO BIO AB (SE) 2003-09-03 EP disclosed
WO-2002046134-A1 NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III KARO BIO AB (SE) 2002-06-13 WO disclosed