Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21495100 | 0.78 | DAO (0.35) | DAOGSK3B | |
| SCHEMBL7068555 | 0.67 | DAO (0.36) | DAOGSK3B | |
| SCHEMBL7070583 | 0.65 | ALOX5 (0.41) | — | |
| SCHEMBL23362973 | 0.65 | DAO (0.39) | DAOGSK3B | |
| SCHEMBL28053261 | 0.65 | DAO (0.34) | DAOGSK3B | |
| SCHEMBL23362972 | 0.65 | DAO (0.39) | DAOGSK3B | |
| SCHEMBL25308367 | 0.64 | DAO (0.39) | DAOGSK3B | |
| SCHEMBL23411290 | 0.64 | DAO (0.47) | DAOGSK3B | |
| SCHEMBL2492030 | 0.64 | MDM2 (0.39) | — | |
| SCHEMBL25308193 | 0.64 | MEN1 (0.47) | DAOGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055479-A1 | COMPOUNDS AND THEIR THERAPEUTIC USE RELATED TO THE PHOSPHORYLATING ACTIVITY OF THE ENZYME GSK-3 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2003-07-10 | — | — | WO | disclosed |