⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680741 | 0.70 | — | — | |
| SCHEMBL3623050 | 0.68 | — | — | |
| SCHEMBL9285114 | 0.63 | — | — | |
| SCHEMBL14740572 | 0.62 | — | — | |
| SCHEMBL17681015 | 0.60 | — | — | |
| SCHEMBL9258011 | 0.58 | — | — | |
| SCHEMBL372616 | 0.58 | — | — | |
| SCHEMBL17858494 | 0.57 | MAOA (0.30) | — | |
| SCHEMBL13725233 | 0.57 | LMNA (0.35) | — | |
| SCHEMBL836656 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246811-B1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS ISLE OF MAN LTD (GB) | 2003-12-03 | — | — | EP | disclosed |
| US-6613919-B2 | Resolution with enantiomerically pure bases such as cinchonidine by forming a salt; also 3,4-dihydroxy-2(5H)-furanones | OXIS ISLE OF MAN | 2003-09-02 | — | — | US | disclosed |
| US-20030065196-A1 | Method for resolving racemic mixtures of 5-substituted 4-hydroxy-2-furanones | OXIS ISLE OF MAN | 2003-04-03 | — | — | US | disclosed |
| EP-1246811-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS Isle of Man, Limited (GB) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049671-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS ISLE OF MAN, LIMITED (US) | 2001-07-12 | — | — | WO | disclosed |
| EP-0336932-A1 | FURANIC POLYOLS, PREPARATION THEREOF AND UTILIZATION IN POLYURETHANES | CENTRE SCIENTIFIQUE ET TECHNIQUE DU BATIMENT (FR) | 1989-10-18 | — | — | EP | disclosed |
| WO-1988004295-A1 | FURANIC POLYOLS, PREPARATION THEREOF AND UTILIZATION IN POLYURETHANES | CENTRE SCIENTIFIQUE ET TECHNIQUE DU BATIMENT (FR) | 1988-06-16 | — | — | WO | disclosed |