SCHEMBL7073511

SCHEMBL7073511

CCCCc1ccc(NC(=O)c2cccc(NC=O)c2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.51
KDR P35968 1/20 0.48
ABCG2 Q9UNQ0 5/20 0.48
POLB P06746 1/20 0.47
ALOX15 P16050 3/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1457071 0.81 RXFP1 (0.56) POLBKDM4EALDH1A1HPGD
SCHEMBL7190666 0.79 TRPV1 (0.61) TRPV1KDRABCG2POLBALOX15
SCHEMBL7160758 0.79 SMO (0.52) POLBKDM4EHPGD
SCHEMBL7080494 0.76 PNLIP (0.62) POLBALOX15KDM4ENPC1RAB9A
SCHEMBL2119500 0.76 FFAR1 (0.66) TRPV1KDRPOLBALOX15KDM4E
SCHEMBL6579934 0.76 PLK1 (0.61) TRPV1ABCG2KDM4E
SCHEMBL14289032 0.76 ABCG2 (0.50) KDRABCG2ALOX15KDM4ENPC1
SCHEMBL7074399 0.76 PNLIP (0.61) POLB
SCHEMBL7554138 0.75 CXCR2 (0.59) KDM4EALDH1A1HPGD
SCHEMBL19077950 0.74 RXFP1 (0.50) ABCG2ALOX15KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP claimed
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP disclosed
US-6548549-B1 Fungicides, insecticides, bactericides; applying to plant BAYER AKTIENGESELLSCHAFT (DE) 2003-04-15 US disclosed
US-6001879-A SUITABLE FOR CONTROLLING PESTS, PREFERABLY FUNGI, INSECTS AND BACTERIA, IN PLANTS AND INDUSTRIAL MATERIALS; METHODS OF THEIR SYBNTHESIS INCLUDING REACTING AMINOSALICYLAMIDES WITH ACYLATING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US disclosed
EP-0848700-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AG (DE) 1998-06-24 EP disclosed
WO-1997008135-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed