SCHEMBL7074399

SCHEMBL7074399

O=CNc1cccc(C(=O)Nc2ccc(Oc3ccccc3)cc2)c1O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 5/20 0.61
STK39 Q9UEW8 1/20 0.53
PGR P06401 1/20 0.52
MAPK1 P28482 1/20 0.52
GFER P55789 1/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
LMNA P02545 2/20 0.48
TGM2 P21980 1/20 0.47
RNF4 P78317 1/20 0.47
TSHR P16473 1/20 0.47
MITF O75030 1/20 0.46
POLB P06746 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080494 0.90 PNLIP (0.62) PNLIPMAPK1GFERMEN1KMT2A
SCHEMBL1457071 0.88 RXFP1 (0.56) MEN1KMT2ALMNAPOLBRXFP1
SCHEMBL7073943 0.87 PKM (0.47) PNLIPMAPK1GFERLMNARXFP1
SCHEMBL1457434 0.86 KMT2A (0.50) PNLIPSTK39MAPK1GFERMEN1
SCHEMBL7077257 0.86 RXFP1 (0.60) STK39RXFP1
SCHEMBL7160758 0.86 SMO (0.52) MEN1KMT2ALMNAPOLBRXFP1
SCHEMBL7074417 0.84 TLR8 (0.49) PNLIPSTK39MAPK1GFERLMNA
SCHEMBL7077402 0.81 PNLIP (0.43) PNLIPMAPK1GFERMEN1KMT2A
SCHEMBL2238659 0.80 PGR (0.49) PNLIPSTK39PGRMAPK1MEN1
SCHEMBL7074805 0.79 PNLIP (0.67) PNLIPSTK39MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP claimed
EP-0848700-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AG (DE) 1998-06-24 EP claimed
WO-1997008135-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO claimed
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP disclosed
US-6548549-B1 Fungicides, insecticides, bactericides; applying to plant BAYER AKTIENGESELLSCHAFT (DE) 2003-04-15 US disclosed
US-6001879-A SUITABLE FOR CONTROLLING PESTS, PREFERABLY FUNGI, INSECTS AND BACTERIA, IN PLANTS AND INDUSTRIAL MATERIALS; METHODS OF THEIR SYBNTHESIS INCLUDING REACTING AMINOSALICYLAMIDES WITH ACYLATING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US disclosed
EP-0848700-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AG (DE) 1998-06-24 EP disclosed
WO-1997008135-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed