Sugi Predict

Sugi Predict / Compounds / SCHEMBL7073569

SCHEMBL7073569

SCHEMBL7073569

C=CCOC(=O)C(=C)C(=O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.66
▸ MAPT P10636 5/20 0.66
▸ CYP3A4 P08684 1/20 0.50
▸ TSHR P16473 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ PKM P14618 1/20 0.43
▸ CES2 O00748 2/20 0.42
▸ CES1 P23141 2/20 0.42
▸ NPSR1 Q6W5P4 3/20 0.41
▸ MAPK1 P28482 2/20 0.41
▸ LMNA P02545 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ EGFR P00533 2/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ AKT1 P31749 1/20 0.40
▸ XBP1 P17861 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1149077 0.88 CYP3A4 (0.55) ALDH1A1MAPTCYP3A4TSHRHSD17B10
SCHEMBL2817243 0.87 ALDH1A1 (0.66) ALDH1A1MAPTSMN1; SMN2CES2CES1
SCHEMBL4610438 0.83 CYP3A4 (0.53) ALDH1A1MAPTCYP3A4TSHRHSD17B10
SCHEMBL9572478 0.80 CYP3A4 (0.46) ALDH1A1MAPTCYP3A4TSHRHSD17B10
SCHEMBL3371353 0.79 MAPT (1.00) ALDH1A1MAPTTSHRSMN1; SMN2CES2
SCHEMBL6241181 0.79 CYP3A4 (0.53) ALDH1A1MAPTCYP3A4TSHRHSD17B10
SCHEMBL19301940 0.78 CYP3A4 (0.51) ALDH1A1MAPTCYP3A4TSHRHSD17B10
SCHEMBL2817246 0.78 ALDH1A1 (0.68) ALDH1A1MAPTSMN1; SMN2CES2CES1
SCHEMBL28343462 0.77 CYP3A4 (0.69) ALDH1A1MAPTCYP3A4TSHRHSD17B10
Benzil SCHEMBL7122126 0.77 CES2 (0.56) ALDH1A1MAPTCYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363869-B1 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES WEYLCHEM LAMOTTE (FR) 2015-04-08 — — EP claimed
EP-1363869-A2 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES Clariant (France) S.A. (FR) 2003-11-26 — — EP claimed
WO-2002067847-A2 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES CLARIANT (FRANCE) (FR) 2002-09-06 — — WO claimed
EP-1363869-B1 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES WEYLCHEM LAMOTTE (FR) 2015-04-08 — — EP disclosed
CN-1243709-C Process for prepn. of alkyl benzoylacrylates CLARIANT FRANCE SA (FR) 2006-03-01 — — CN disclosed
CN-1243709-C Process for prepn. of alkyl benzoylacrylates CLARIANT FRANCE SA (FR) 2006-03-01 — — CN disclosed
CN-1500074-A Process for prepn. of alkyl benzoylacrylates 克莱里安特法国公司 2004-05-26 — — CN disclosed
CN-1500074-A Process for prepn. of alkyl benzoylacrylates 克莱里安特法国公司 2004-05-26 — — CN disclosed
EP-1363869-A2 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES Clariant (France) S.A. (FR) 2003-11-26 — — EP disclosed
EP-1363869-A2 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES Clariant (France) S.A. (FR) 2003-11-26 — — EP disclosed
WO-2002067847-A3 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES CLARIANT FRANCE SA (FR) 2002-12-05 — — WO disclosed
WO-2002067847-A2 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES CLARIANT (FRANCE) (FR) 2002-09-06 — — WO disclosed
WO-2002067847-A2 PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES CLARIANT (FRANCE) (FR) 2002-09-06 — — WO disclosed