Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936870 | 0.84 | TRPA1 (0.50) | ELANECTSGTRPA1ALDH1A1TSHR | |
| SCHEMBL2936995 | 0.82 | TRPA1 (0.50) | ELANECTSGTRPA1ALDH1A1TSHR | |
| SCHEMBL2939962 | 0.79 | ALOX15 (0.57) | TRPA1ALDH1A1TSHRALOX15CSNK2A2 | |
| SCHEMBL2938543 | 0.79 | ALOX15 (0.57) | TRPA1ALDH1A1TSHRALOX15CSNK2A2 | |
| SCHEMBL2939822 | 0.77 | ALDH1A1 (0.45) | ELANETRPA1ALDH1A1TSHRALOX15 | |
| SCHEMBL2937969 | 0.76 | TRPA1 (0.42) | ELANECTSGTRPA1ALDH1A1TSHR | |
| SCHEMBL2938830 | 0.74 | TRPA1 (0.45) | ELANECTSGTRPA1ALDH1A1TSHR | |
| SCHEMBL2937049 | 0.74 | MCL1 (0.41) | ELANECTSGTRPA1ALDH1A1TSHR | |
| SCHEMBL30839716 | 0.73 | CD44 (0.65) | TRPA1ALDH1A1TSHRALOX15CD44 | |
| SCHEMBL3462069 | 0.73 | CD44 (0.65) | TRPA1ALDH1A1TSHRALOX15CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002801-B1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | SOLVIAS AG (CH) | 2003-06-18 | — | — | EP | claimed |
| EP-1002801-B1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | SOLVIAS AG (CH) | 2003-06-18 | — | — | EP | disclosed |