SCHEMBL7073758

SCHEMBL7073758

Cc1cc(O)cc(Cl)c1OCCCOc1ccc(C(F)(F)F)cn1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
MRGPRX4 Q96LA9 1/20 0.41
GABRA5 P31644 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 1/20 0.38
HPGD P15428 2/20 0.38
LIPE Q05469 4/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7072961 0.98 MRGPRX4 (0.43) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL7071031 0.92 KMT2A (0.46) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL7073751 0.89 MRGPRX4 (0.47) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL7078746 0.88 MRGPRX4 (0.46) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL7076311 0.88 MRGPRX4 (0.46) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL7073314 0.88 KMT2A (0.47) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL4624147 0.86 KMT2A (0.41) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL7076194 0.85 MRGPRX4 (0.45) MRGPRX4GABRA5MAPK1SMN1; SMN2TSHR
SCHEMBL7716830 0.84 HPGD (0.41) KMT2AMRGPRX4GABRA5L3MBTL1MAPK1
SCHEMBL8408847 0.83 PPARA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP claimed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US claimed
CN-1169147-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1997-12-31 CN claimed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP claimed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO claimed
CN-1217933-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2005-09-07 CN disclosed
CN-1654455-A Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2005-08-17 CN disclosed
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
CN-1088061-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2002-07-24 CN disclosed
CN-1318535-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2001-10-24 CN disclosed
US-6268313-B1 CONTROLLING INSECTS, MITES, TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-31 US disclosed
US-6071861-A FOR THE CONTROL OF NOXIOUS INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, INC. (JP) 2000-06-06 US disclosed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
CN-1169147-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1997-12-31 CN disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC KMT2A 2833/4885MRGPRX4 1668/4885GABRA5 2050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.