Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29223134 | 0.90 | LMNA (0.54) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL31732807 | 0.83 | LMNA (0.59) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL1102399 | 0.83 | LMNA (0.59) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL12915399 | 0.81 | LMNA (0.69) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| Iodide SCHEMBL10722209 | 0.81 | LMNA (0.58) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL9565192 | 0.81 | ADRA2A (0.55) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL29449584 | 0.80 | LMNA (0.58) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL7381646 | 0.79 | LMNA (0.65) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL27895641 | 0.79 | LMNA (0.65) | LMNANCOA3NPC1RAB9ACYP2A6 | |
| SCHEMBL14463771 | 0.79 | LMNA (1.00) | LMNANCOA3NPC1RAB9ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558392-A1 | Process for the stabilisation of a charge transfer complex based on 7,7,8,8-tetracyanoquinodimethane | COMPAGNIE EUROPEENNE DE COMPOSANTS ELECTRONIQUES LCC (FR) | 1993-09-01 | — | — | EP | claimed |
| WO-2003059928-A1 | POLYNUCLEOTIDE ENCODING AN AP-2 DOMAIN TRANSCRIPTION FACTOR | AVESTHA GENGRAINE TECHNOLOGIES PVT. LTD. (IN) | 2003-07-24 | — | — | WO | disclosed |
| EP-0558392-A1 | Process for the stabilisation of a charge transfer complex based on 7,7,8,8-tetracyanoquinodimethane | COMPAGNIE EUROPEENNE DE COMPOSANTS ELECTRONIQUES LCC (FR) | 1993-09-01 | — | — | EP | disclosed |