Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074173 | 0.88 | MEN1 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7074257 | 0.87 | F10 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7649509 | 0.84 | GAA (0.61) | GPR55KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7076585 | 0.83 | TSHR (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7072206 | 0.81 | F10 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7075379 | 0.79 | POLB (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7071445 | 0.78 | F10 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7074841 | 0.78 | KMT2A (0.45) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL7071711 | 0.76 | F10 (0.48) | KMT2AMEN1ALDH1A1PLAU | |
| SCHEMBL7074669 | 0.74 | TSHR (0.56) | ALDH1A1SMN1; SMN2TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-1025086-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999016751-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 1999-04-08 | — | — | WO | disclosed |