Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074173 | 0.91 | MEN1 (0.53) | MEN1KMT2ANPC1MAPTLMNA | |
| SCHEMBL7074257 | 0.90 | F10 (0.53) | F10MEN1KMT2AMAPTLMNA | |
| SCHEMBL7651047 | 0.86 | F10 (0.58) | F10MEN1KMT2AMAPTLMNA | |
| SCHEMBL7074005 | 0.81 | GPR55 (0.52) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL6737341 | 0.81 | F10 (0.77) | F10 | |
| Hydrochloric Acid SCHEMBL5736315 | 0.80 | F10 (0.61) | F10MAPTLMNAGAA | |
| Hydrochloric Acid SCHEMBL5733561 | 0.80 | F10 (0.75) | F10 | |
| SCHEMBL7074052 | 0.79 | F10 (0.56) | F10MEN1KMT2AMAPTLMNA | |
| SCHEMBL7070051 | 0.79 | LMNA (0.52) | F10MAPTLMNAGAATP53 | |
| SCHEMBL7076585 | 0.79 | TSHR (0.47) | MEN1KMT2AMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |