Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654095 | 0.84 | GAA (0.53) | KMT2AMEN1MAPK1POLBNPSR1 | |
| SCHEMBL7074173 | 0.79 | MEN1 (0.53) | KMT2AMEN1POLBPLAUHPN | |
| SCHEMBL7075110 | 0.79 | LMNA (0.49) | KMT2AMEN1MAPK1POLBMAPT | |
| SCHEMBL7074257 | 0.79 | F10 (0.53) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL7071435 | 0.78 | KMT2A (0.64) | KMT2AMEN1MAPK1POLBNPSR1 | |
| SCHEMBL7074005 | 0.78 | GPR55 (0.52) | KMT2AMEN1POLBPLAUHPN | |
| SCHEMBL7076585 | 0.77 | TSHR (0.47) | KMT2AMEN1MAPK1PLAUHPN | |
| SCHEMBL7072206 | 0.77 | F10 (0.52) | KMT2AMEN1POLBPLAUALDH1A1 | |
| SCHEMBL7073684 | 0.77 | F2 (0.55) | KMT2AMEN1MAPK1POLBNPSR1 | |
| SCHEMBL7651893 | 0.74 | KMT2A (0.53) | KMT2AMEN1MAPK1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-1025086-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999016751-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 1999-04-08 | — | — | WO | disclosed |