Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL4870083 | 0.88 | MAPT (0.49) | HSD17B10TSHRTDP1MAPTPKM | |
| Morpholine SCHEMBL6677436 | 0.86 | TSHR (0.68) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| Pyrrolidine SCHEMBL7079209 | 0.85 | HSD17B10 (0.71) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| Fluoride SCHEMBL28101861 | 0.82 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL26788 | 0.80 | HSD17B10 (1.00) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL29859415 | 0.80 | HSD17B10 (1.00) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL11125458 | 0.78 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8044782 | 0.78 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| Bromide SCHEMBL28560244 | 0.78 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL9579917 | 0.78 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003504-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | EP | disclosed |