Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075112 | 0.87 | KMT2A (0.59) | TGM2KMT2AATMF10F2 | |
| SCHEMBL7074867 | 0.86 | TGM2 (0.55) | TGM2KMT2AF10F2PRSS1 | |
| Acetic Acid SCHEMBL27530351 | 0.85 | KMT2A (0.56) | TGM2KMT2AATMF10F2 | |
| SCHEMBL17076474 | 0.82 | TGM2 (0.68) | TGM2KMT2AATMF10F2 | |
| SCHEMBL7071366 | 0.80 | F2 (0.51) | KMT2AF10F2PRSS1TPSAB1 | |
| SCHEMBL7077596 | 0.80 | TGM2 (0.52) | TGM2KMT2AATMGAAPKM | |
| SCHEMBL571878 | 0.80 | TGM2 (0.68) | TGM2KMT2AATMF2PRSS1 | |
| SCHEMBL29181102 | 0.78 | TGM2 (0.69) | TGM2KMT2AATMF10SPR | |
| SCHEMBL18711519 | 0.77 | KMT2A (0.71) | TGM2KMT2AATMF2PRSS1 | |
| SCHEMBL27571758 | 0.77 | KMT2A (0.71) | TGM2KMT2AATMF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |