Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074199 | 0.86 | TGM2 (0.58) | TGM2KMT2AF2PRSS1TPSAB1 | |
| SCHEMBL10064240 | 0.86 | GAA (0.64) | TGM2CNR1GPR183KMT2AMEN1 | |
| SCHEMBL7071342 | 0.85 | CNR1 (0.57) | TGM2CNR1GPR183KMT2AMEN1 | |
| SCHEMBL7071366 | 0.85 | F2 (0.51) | CNR1KMT2AF2PRSS1TPSAB1 | |
| SCHEMBL7074851 | 0.83 | GAA (0.63) | CNR1KMT2AF2PRSS1TPSAB1 | |
| SCHEMBL4277156 | 0.83 | CNR1 (0.63) | TGM2CNR1GPR183KMT2AMEN1 | |
| SCHEMBL7074428 | 0.82 | PKM (0.62) | CNR1KMT2AMEN1F2PRSS1 | |
| Acetic Acid SCHEMBL27538655 | 0.82 | CNR1 (0.53) | TGM2CNR1GPR183KMT2AMEN1 | |
| SCHEMBL7075152 | 0.79 | CNR1 (0.51) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7070017 | 0.79 | DGAT1 (0.50) | TGM2CNR1GPR183KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |