Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 5/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27530351 | 0.97 | KMT2A (0.56) | KMT2AATMTGM2F10SPR | |
| SCHEMBL7074199 | 0.87 | TGM2 (0.58) | KMT2AATMTGM2F10SPR | |
| SCHEMBL7071342 | 0.85 | CNR1 (0.57) | KMT2AATMTGM2F10LMNA | |
| Acetic Acid SCHEMBL27538655 | 0.83 | CNR1 (0.53) | KMT2ATGM2F10SPRSMN1; SMN2 | |
| SCHEMBL18711519 | 0.81 | KMT2A (0.71) | KMT2AATMTGM2SPRSMN1; SMN2 | |
| SCHEMBL27571758 | 0.81 | KMT2A (0.71) | KMT2AATMTGM2SPRSMN1; SMN2 | |
| SCHEMBL25531 | 0.80 | KMT2A (0.88) | KMT2AATMTGM2SMN1; SMN2F2 | |
| SCHEMBL29437927 | 0.80 | KMT2A (0.88) | KMT2AATMTGM2SMN1; SMN2F2 | |
| SCHEMBL17076474 | 0.79 | TGM2 (0.68) | KMT2AATMTGM2F10SPR | |
| SCHEMBL7076710 | 0.79 | MGLL (0.51) | KMT2AATMTGM2SPRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |