Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074221 | 1.00 | ACE (0.47) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL22686106 | 0.96 | CTSS (0.48) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL22686097 | 0.92 | CTSS (0.45) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL22348905 | 0.92 | CTSS (0.45) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL23056573 | 0.89 | HDAC1 (0.40) | CTSSCTSLCTSBHDAC1HDAC6 | |
| SCHEMBL21895863 | 0.89 | CTSS (0.43) | CTSSCTSLCTSBCTSK | |
| SCHEMBL16288777 | 0.89 | HDAC1 (0.38) | ACECTSSCTSLCTSBHDAC1 | |
| SCHEMBL21895861 | 0.89 | CTSS (0.43) | CTSSCTSLCTSBCTSK | |
| SCHEMBL15083394 | 0.89 | HDAC1 (0.38) | ACECTSSCTSLCTSBHDAC1 | |
| SCHEMBL20630582 | 0.88 | CTSL (0.46) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059926-A2 | METHODS AND COMPOSITIONS FOR AMINOACYL-tRNA SYNTHESIS | UNIVERSITY OF MASSACHUSETTS (US) | 2003-07-24 | — | — | WO | disclosed |