Ethylene

Ethylene

SCHEMBL707435

C=C.O=S(=O)(O)C(Br)S(=O)(=O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1749147 0.72
SCHEMBL11744277 0.67
SCHEMBL318116 0.67
Sulfuric Acid SCHEMBL29131640 0.66
Sulfuric Acid SCHEMBL28537753 0.66 CA5A (0.75) CA5ACA5B
Sulfuric Acid SCHEMBL27667344 0.66 CA5A (0.75) CA5ACA5B
Sulfuric Acid SCHEMBL11255468 0.66 CA5A (0.75) CA5ACA5B
Sulfuric Acid SCHEMBL31435537 0.66 CA5A (0.75) CA5ACA5B
Sulfuric Acid SCHEMBL562189 0.66
Sulfuric Acid SCHEMBL28681208 0.66 CA5A (0.75) CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124793-B2 Derivatives of ethylene methanedisulfonate as cancer chemotherapeutic agents CRONYN MARSHALL W (US) 2012-02-28 US disclosed
US-20090176805-A1 DERIVATIVES OF ETHYLENE METHANEDISULFONATE AS CANCER CHEMOTHERAPEUTIC AGENTS CRONYN MARSHALL W 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090176805-A1 DERIVATIVES OF ETHYLENE METHANEDISULFONATE AS CANCER CHEMOTHERAPEUTIC AGENTS MGMT, ETV6, EI24 CA5A 975/4885CA5B 1131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.