Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27530029 | 0.95 | F10 (0.61) | F10CA12CA1CA2CA7 | |
| SCHEMBL7076666 | 0.88 | LMNA (0.72) | F10MAPTL3MBTL1MAPK1LMNA | |
| SCHEMBL7077553 | 0.88 | F10 (0.65) | F10CA12CA1CA2CA7 | |
| SCHEMBL7074220 | 0.88 | LMNA (0.71) | F10CA12CA1CA2CA7 | |
| SCHEMBL7126859 | 0.88 | ALDH1A1 (0.62) | F10MAPTL3MBTL1MAPK1LMNA | |
| SCHEMBL7071445 | 0.86 | F10 (0.62) | F10CA12CA1CA2CA7 | |
| SCHEMBL10717731 | 0.85 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10674722 | 0.85 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7074608 | 0.85 | F10 (0.61) | F10MAPTL3MBTL1MAPK1LMNA | |
| SCHEMBL7069343 | 0.85 | F10 (0.61) | F10CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |