Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27525154 | 0.97 | ALDH1A1 (0.59) | ALDH1A1GAATSHRKMT2ALMNA | |
| SCHEMBL7074494 | 0.88 | F10 (0.66) | KMT2ALMNAMEN1F10MAPT | |
| SCHEMBL7076666 | 0.86 | LMNA (0.72) | ALDH1A1GAAKMT2ALMNAMEN1 | |
| SCHEMBL7077553 | 0.86 | F10 (0.65) | KMT2ALMNAMEN1F10MAPT | |
| Acetic Acid SCHEMBL27530029 | 0.86 | F10 (0.61) | ALDH1A1TSHRKMT2ALMNAMEN1 | |
| Acetic Acid SCHEMBL27552344 | 0.85 | F10 (0.60) | KMT2ALMNAMEN1F10MAPT | |
| SCHEMBL7069367 | 0.84 | F2 (0.54) | ALDH1A1GAATSHRKMT2ALMNA | |
| SCHEMBL7074220 | 0.84 | LMNA (0.71) | ALDH1A1GAAKMT2ALMNAMEN1 | |
| SCHEMBL7069343 | 0.83 | F10 (0.61) | ALDH1A1TSHRLMNAPKMF10 | |
| SCHEMBL7074321 | 0.83 | CA12 (0.65) | ALDH1A1KMT2ALMNAMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |