Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574389 | 0.85 | LMNA (0.44) | KDM4EMEN1KMT2AMPOALDH1A1 | |
| SCHEMBL5922323 | 0.72 | NOTUM (0.51) | POLBKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5922329 | 0.71 | NOTUM (0.56) | POLBKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL154613 | 0.69 | NPC1 (0.66) | POLBKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2553094 | 0.69 | NPC1 (0.66) | POLBKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29399711 | 0.69 | NPC1 (0.66) | POLBKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5922382 | 0.68 | NOTUM (0.54) | POLBKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7290818 | 0.68 | ALDH1A1 (0.51) | POLBKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31336165 | 0.68 | ALDH1A1 (0.51) | POLBKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12546032 | 0.68 | SMN1; SMN2 (0.56) | POLBKDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278784-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2003-01-29 | — | — | EP | disclosed |
| CN-1347423-A | Catalyst contg. N-pyrrolyl substd. nitrogen donors | EASTMAN CHEM CO (US) | 2002-05-01 | — | — | CN | disclosed |
| EP-1192189-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001083571-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2000050470-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |