SCHEMBL7074741

SCHEMBL7074741

Cc1nnc(Br)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.43
ESR1 P03372 1/20 0.43
GPR3 P46089 1/20 0.41
POLB P06746 3/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RXFP1 Q9HBX9 2/20 0.37
ENPP3 O14638 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
GFER P55789 1/20 0.37
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29717228 1.00 SMN1; SMN2 (0.47) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1
SCHEMBL3260315 0.84 GPR3 (0.45) SMN1; SMN2NPC1RAB9AALDH1A1GPR3
SCHEMBL30578353 0.84 GPR3 (0.45) SMN1; SMN2NPC1RAB9AALDH1A1GPR3
SCHEMBL89446 0.84 SMN1; SMN2 (0.58) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL27658861 0.82 SMN1; SMN2 (0.56) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1
SCHEMBL28982421 0.75 GPR3 (0.38) SMN1; SMN2KMT2AALDH1A1MEN1GPR3
SCHEMBL2306302 0.71 MEN1 (0.50) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1
SCHEMBL5385941 0.71 SMN1; SMN2 (0.47) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1
SCHEMBL599376 0.71 IDO1 (0.36) SMN1; SMN2KMT2AALDH1A1MEN1GPR3
SCHEMBL17153810 0.71 SMN1; SMN2 (0.47) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-3265447-B1 BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-03-01 EP disclosed
WO-2022125989-A1 COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS SCRIPPS RESEARCH INSTITUTE, THE (US) 2022-06-16 WO disclosed
CN-107428708-B Benzoxazine low temperature curable compositions 亨斯迈先进材料美国有限责任公司 2021-11-09 CN disclosed
US-20180030264-A1 Benzoxazine Low Temperature Curable Composition HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2018-02-01 US disclosed
CN-107428708-A Benzoxazine low temperature cure composition 亨斯迈先进材料美国有限责任公司 2017-12-01 CN disclosed
CN-104177435-A Red phosphorescence iridium complexes, preparing method thereof and organic electroluminescence device OCEANS KING LIGHTING SCIENCE 2014-12-03 CN disclosed
CN-104177434-A Red phosphorescence iridium complexes, preparing method thereof and organic electroluminescence device OCEANS KING LIGHTING SCIENCE 2014-12-03 CN disclosed
CN-104178114-A Red phosphorescence iridium complexes, preparing method thereof and organic electroluminescence device OCEANS KING LIGHTING SCIENCE 2014-12-03 CN disclosed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
EP-0328020-B1 Use of a catalyst in epoxy compositions DOW CHEMICAL CO (US) 1996-10-09 EP disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
CN-1118794-A Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 1996-03-20 CN disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030264-A1 Benzoxazine Low Temperature Curable Composition CRYZ, PIEZO1, PSMD12 SMN1; SMN2 755/4885NPC1 4727/4885RAB9A 4260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.