Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855445 | 0.85 | LMNA (0.62) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL2900297 | 0.84 | LMNA (0.60) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL27598271 | 0.82 | LMNA (0.59) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL26250266 | 0.81 | TSHR (0.57) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL4758947 | 0.79 | LMNA (0.65) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL14838471 | 0.79 | LMNA (0.50) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL16011210 | 0.79 | LMNA (0.50) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL28363239 | 0.79 | LMNA (0.56) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL12216197 | 0.79 | LMNA (0.56) | LMNAPOLBTP53GAAKMT2A | |
| SCHEMBL1744782 | 0.78 | RAB9A (0.66) | LMNAPOLBTP53GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-5180419-A | Herbicidal 2-(2-imidazolin-2-yl)-benzo-(5-membered)-heterocycles and the use thereof | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |