Dimedazol

Dimedazol

SCHEMBL7074847

CCCCCCCCCCCCCCCCCCN(C)CCCCCCCCCCCCCCCCCC.Cc1cc2nc[nH]c2cc1C.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
QPCT Q16769 2/20 0.32
MAPT P10636 1/20 0.32
KDM5A P29375 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL217445 0.83 EPHX1 (0.34) EPHX1QPCTKDM5A
Dimedazol SCHEMBL727732 0.78 MAPT (0.40) QPCTMAPT
SCHEMBL15232140 0.78 EPHX1 (0.37) EPHX1QPCTMAPT
SCHEMBL7075653 0.77 HTT (0.30) KDM5A
SCHEMBL7072436 0.72 KDM4E (0.47) MAPT
Imidazole SCHEMBL7070534 0.72 ALDH1A1 (0.33) KDM5A
1,2,4-Triazole SCHEMBL7076445 0.72 HTR7 (0.31)
Dimedazol SCHEMBL61387 0.68 MAPT (0.45) QPCTMAPT
SCHEMBL7072003 0.67 S1PR2 (0.34) KDM5A
SCHEMBL61792 0.65 HRH3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056752-B1 Catalyst activators comprising expanded anions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-25 EP disclosed
US-6462156-B2 AS POLYMERIZATION CATALYST FOR PRODUCING OLEFIN POLYMERS THE DOW CHEMICAL COMPANY 2002-10-08 US disclosed
US-20020132729-A1 Catalyst activators comprising expanded anions LAPOINTE ROBERT E (US) 2002-09-19 US disclosed
US-6395671-B2 ANION CONTAINING TWO LEWIS BASIC SITES WHICH ARE COORDINATED TO LEWIS ACIDS; FOR OLEFIN POLYMERIZATION THE DOW CHEMICAL COMPANY 2002-05-28 US disclosed
US-20010027161-A1 Catalyst activators comprising expanded anions THE DOW CHEMICAL COMPANY 2001-10-04 US disclosed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP disclosed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO disclosed