Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457103 | 0.79 | L3MBTL1 (0.50) | ALOX5POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL267054 | 0.70 | ALOX5 (0.61) | ALOX5PKMATMALDH1A1L3MBTL1 | |
| SCHEMBL7073440 | 0.70 | ATM (0.48) | ALOX5PKMATMALDH1A1LMNA | |
| SCHEMBL31291527 | 0.70 | L3MBTL1 (0.56) | ALOX5POLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7074014 | 0.69 | ATM (0.45) | ALOX5PKMATMALDH1A1L3MBTL1 | |
| SCHEMBL10024168 | 0.67 | L3MBTL1 (0.50) | ALOX5POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL3096606 | 0.67 | MERTK (0.51) | ALOX5PKM | |
| SCHEMBL13156526 | 0.67 | MERTK (0.51) | ALOX5PKM | |
| SCHEMBL9637883 | 0.66 | EPHX2 (0.62) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4760506 | 0.66 | HDAC4 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091932-B1 | CHIRAL STATIONARY PHASES FOR ENANTIOMERS SEPARATION AND THEIR PREPARATION | EURAND PHARMACEUTICALS LTD (IE) | 2003-06-25 | — | — | EP | disclosed |
| US-6437167-B1 | CHROMATOGRAPHIC COLUMNS FOR ANALYTICAL AND PREPARATIVE SEPARATION OF ENANTIOMERS; INTRODUCTION OF CHIRAL GROUPS ON 1,3-DICYANO-2,4,5,6-TETRACHLOROBENZENE BY SUBSTITUTION OF CHLORINE ATOMS, SPACER GROUP | SOCIETA' COOPERATIVE CENTRO RICERCHE POLYTECH A RESPONSABILITIA' LIMITATA (IT) | 2002-08-20 | — | — | US | disclosed |