⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15121235 | 0.84 | MEN1 (0.31) | — | |
| SCHEMBL25275692 | 0.81 | — | — | |
| SCHEMBL367403 | 0.72 | — | — | |
| SCHEMBL43130 | 0.69 | — | — | |
| SCHEMBL28904420 | 0.69 | — | — | |
| SCHEMBL332010 | 0.67 | — | — | |
| SCHEMBL9153045 | 0.67 | — | — | |
| SCHEMBL7122826 | 0.67 | — | — | |
| SCHEMBL7114754 | 0.67 | — | — | |
| SCHEMBL5217414 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010666-A | Nitro-mimic functional group substituted polynitroazole energetic compound and application thereof | 北京理工大学 | 2022-09-06 | — | — | CN | claimed |
| US-9493799-B2 | In vivo and in vitro olefin cyclopropanation catalyzed by heme enzymes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-11-15 | — | — | US | claimed |
| EP-1082297-B1 | SUBSTITUTED DITHIO-BIS-NITROBENZENES AND THEIR APPLICATIONS | PASTEUR INSTITUT (FR) | 2003-06-18 | — | — | EP | claimed |
| EP-0031548-B1 | PROCESS FOR PREPARING 5-AMINO-1,2,3-THIADIAZOLES | UBE INDUSTRIES, LTD. (JP) | 1983-03-23 | — | — | EP | claimed |
| US-20240228488-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-11 | — | — | US | disclosed |
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2024060966-A1 | PAN-KRAS INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2024-03-28 | — | — | WO | disclosed |
| WO-2024002375-A1 | COMPOUND FUNCTIONING AS SMARCA2/4 INHIBITOR AND USE THEREOF | 甘李药业股份有限公司 | 2024-01-04 | — | — | WO | disclosed |
| US-20230398223-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-12-14 | — | — | US | disclosed |
| US-20230303526-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-09-28 | — | — | US | disclosed |
| US-11739074-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230250110-A1 | DEUTERATED IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-08-10 | — | — | US | disclosed |
| US-7834009-B2 | 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| US-20100248264-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
| US-20090062263-A1 | treating hepatitis C virus infections; inhibitor of HCV NS5B polymerase; N-{3-[1-(4-Fluoro-benzyl)-4-hydroxy-5-(3-methyl-butyl)-2-oxo-1,2,5,6-tetrahydro-pyridin-3-yl]-1,1-dioxo-1,4-dihydro-1(lambda 6)-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide; coadministering with additional therapeutic agent | ANADYS PHARMACEUTICALS, INC. | 2009-03-05 | — | — | US | disclosed |
| US-20080306109-A1 | Indolizine Derivatives as Ligands of the Crth2 Receptor | ARGENTA DISCOVERY LIMITED (GB) | 2008-12-11 | — | — | US | disclosed |
| US-20080227152-A1 | Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-18 | — | — | US | disclosed |
| US-4609495-A | BETA-LACTAMASE INHIBITORS, ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1986-09-02 | — | — | US | disclosed |
| US-4548815-A | SYNERGISTIC MIXTURE OF AN OXAPENICILLIN AND A PENICILLIN | BEECHAM GROUP P.L.C. (GB) | 1985-10-22 | — | — | US | disclosed |
| US-4228174-A | ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1980-10-14 | — | — | US | disclosed |