⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082507 | 0.79 | — | — | |
| SCHEMBL23113780 | 0.74 | FAAH (0.69) | — | |
| SCHEMBL11252256 | 0.72 | FAAH (0.53) | — | |
| SCHEMBL7839616 | 0.72 | — | — | |
| SCHEMBL5204758 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL17941109 | 0.72 | — | — | |
| SCHEMBL962322 | 0.71 | GAA (0.54) | — | |
| SCHEMBL9572473 | 0.70 | — | — | |
| SCHEMBL81647 | 0.70 | — | — | |
| Butane SCHEMBL11012887 | 0.70 | FAAH (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250164511-A1 | Diazobutanone Linker - Assisted High-Throughput Quantitative Analysis for Phosphate and Sulfate Containing Lipids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2025-05-22 | — | — | US | disclosed |
| US-20250164511-A1 | Diazobutanone Linker - Assisted High-Throughput Quantitative Analysis for Phosphate and Sulfate Containing Lipids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2025-05-22 | — | — | US | disclosed |
| US-20240228488-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20240208985-A2 | ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-06-27 | — | — | US | disclosed |
| CN-118059153-A | Composition for improving acne skin | 株式会社LG生活健康 | 2024-05-24 | — | — | CN | disclosed |
| US-20230133119-A1 | ANDROGEN RECEPTOR REGULATION BY SMALL MOLECULE ENANTIOMERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2023-05-04 | — | — | US | disclosed |
| US-10392389-B2 | Heterocyclic compounds for the inhibition of PASK | BIOENERGENIX LLC (US) | 2019-08-27 | — | — | US | disclosed |
| US-20150284395-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX LLC | 2015-10-08 | — | — | US | disclosed |
| US-20150284395-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX LLC | 2015-10-08 | — | — | US | disclosed |
| WO-2014066795-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2014-05-01 | — | — | WO | disclosed |
| US-8586550-B2 | Thiazole derivatives as SGLT2 inhibitors and pharmaceutical composition comprising same | GREEN CROSS CORPORATION (KR) | 2013-11-19 | — | — | US | disclosed |
| US-20130090298-A1 | Thiazole Derivatives as SGLT2 Inhibitors and Pharmaceutical Composition Comprising Same | GREEN CROSS CORPORATION (KR) | 2013-04-11 | — | — | US | disclosed |
| US-7423132-B2 | Method for the enrichment and characterization of phosphorylated peptides or proteins | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-09-09 | — | — | US | disclosed |
| CN-1214717-A | Coating composition comprising bicyclo- or spiro-orthoester-functional compound | AKZO NOBEL NV (NL) | 1999-04-21 | — | — | CN | disclosed |
| US-5389491-A | Negative working resist composition | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0095345-B1 | TETRAHYDRO-3,5-DIOXO-1H-PYRROLIZINE-7A(5H)-CARBOXYLIC ACIDS AND DERIVATIVES AS COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| US-4607043-A | SENILITY, AMNESIA | WARNER-LAMBERT COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4547519-A | Tetrahydro-3,5-dioxo-1H-pyrrolizine-7a(5H)-carboxylic acid and benzyl esters and amides thereof and their use in reversing amnesia | WARNER-LAMBERT COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0095345-A2 | Tetrahydro-3,5-dioxo-1H-pyrrolizine-7a(5H)-carboxylic acids and derivatives as cognition activators | WARNER-LAMBERT COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |