SCHEMBL7122826

SCHEMBL7122826

CNC(=O)C=[N+]=[N-]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334738 0.69 ALDH1A1 (0.32)
SCHEMBL18130360 0.67
SCHEMBL7074997 0.67
SCHEMBL332010 0.67
SCHEMBL6963893 0.65
SCHEMBL2486077 0.65 CHRNB2 (0.44)
SCHEMBL1630764 0.65 CHRNB2 (0.44)
SCHEMBL1630761 0.65 CHRNB2 (0.44)
SCHEMBL13108979 0.63
Nitrogen SCHEMBL29248631 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230286920-A1 CYCLOOCTYNES FOR CLICK CHEMISTRY MASSACHUSETTS INST TECHNOLOGY (US) 2023-09-14 US disclosed
US-20230286920-A1 CYCLOOCTYNES FOR CLICK CHEMISTRY MASSACHUSETTS INST TECHNOLOGY (US) 2023-09-14 US disclosed
US-11673865-B2 Cyclooctynes for click chemistry MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-13 US disclosed
US-11673865-B2 Cyclooctynes for click chemistry MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-13 US disclosed
US-20220402876-A1 CYCLOOCTYNES FOR CLICK CHEMISTRY MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2022-12-22 US disclosed
WO-2022250679-A1 CYCLOOCTYNES FOR CLICK CHEMISTRY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-12-01 WO disclosed
US-11377424-B1 Cyclooctynes for click chemistry MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-07-05 US disclosed
US-10676449-B2 Electronically activated strained alkynes WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-06-09 US disclosed
US-20190233385-A1 ELECTRONICALLY ACTIVATED STRAINED ALKYNES WISCONSIN ALUMNI RESEARCH FOUNDATION 2019-08-01 US disclosed
EP-1038866-B1 Process for producing aziridine compound DAICEL CHEM (JP) 2003-11-12 EP disclosed
US-6323346-B1 REACTING A DIAZOACETIC ACID DERIVATIVE OF THE FORMULA N.SUB.2 CHR.SUP.4 WITH A CARBONYL COMPOUND OF FORMULA R.SUP.1 R.SUP.2 C.DBD.O AND AN AMINO-GROUP-CONTAINING COMPOUND OF FORMULA R.SUP.3 NH.SUB.2 IN THE PRESENCE OF AN IRIDIUM COMPLEX DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-11-27 US disclosed
EP-1038866-A1 Process for producing aziridine compound Daicel Chemical Industries, Ltd. (JP) 2000-09-27 EP disclosed