Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076839 | 0.86 | KMT2A (0.59) | HDAC4HDAC6KMT2AMEN1MAPK1 | |
| SCHEMBL7074627 | 0.85 | TSHR (0.57) | HDAC4HDAC6DGAT1MAPK1THRB | |
| SCHEMBL7069975 | 0.84 | GAA (0.60) | HDAC4HDAC6DGAT1KMT2AMAPK1 | |
| SCHEMBL7076669 | 0.83 | GAA (0.53) | HDAC4HDAC6DGAT1KMT2ATHRB | |
| SCHEMBL7075108 | 0.83 | GAA (0.48) | HDAC4HDAC6DGAT1PKMALDH1A1 | |
| SCHEMBL7652755 | 0.83 | MAPT (0.59) | DGAT1KMT2AMEN1THRBALDH1A1 | |
| SCHEMBL7074100 | 0.82 | MAPT (0.53) | HDAC4HDAC6DGAT1THRBPKM | |
| SCHEMBL7069977 | 0.82 | PKM (0.55) | DGAT1KMT2AMEN1MAPK1PKM | |
| SCHEMBL7074802 | 0.82 | HDAC4 (0.53) | HDAC4HDAC6DGAT1MAPK1THRB | |
| SCHEMBL7071584 | 0.82 | GAA (0.52) | HDAC4HDAC6DGAT1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |