Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076839 | 0.86 | KMT2A (0.59) | MAPTPOLBLMNAGAATHRB | |
| SCHEMBL7075110 | 0.86 | LMNA (0.49) | MAPTPOLBLMNATHRBMEN1 | |
| SCHEMBL7655621 | 0.83 | LMNA (0.57) | MAPTPOLBLMNADGAT1GAA | |
| SCHEMBL7075151 | 0.83 | HDAC4 (0.49) | MAPTLMNADGAT1GAATHRB | |
| SCHEMBL7654110 | 0.82 | LMNA (0.53) | MAPTPOLBLMNADGAT1GAA | |
| SCHEMBL7648189 | 0.81 | LMNA (0.53) | MAPTPOLBLMNADGAT1GAA | |
| SCHEMBL7070001 | 0.81 | THRB (0.63) | MAPTPOLBLMNADGAT1GAA | |
| SCHEMBL7649347 | 0.80 | LMNA (0.53) | MAPTPOLBLMNADGAT1GAA | |
| SCHEMBL7654095 | 0.78 | GAA (0.53) | MAPTPOLBGAAALDH1A1NPC1 | |
| SCHEMBL7074329 | 0.77 | MAPT (0.59) | MAPTPOLBLMNADGAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |