SCHEMBL7075375

SCHEMBL7075375

Cc1cc(O)cc(Cl)c1OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.56
KDM4E B2RXH2 1/20 0.48
THRB P10828 2/20 0.47
MAPT P10636 2/20 0.47
TP53 P04637 1/20 0.47
GAA P10253 1/20 0.47
LMNA P02545 3/20 0.47
HPGD P15428 1/20 0.47
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
POLB P06746 1/20 0.44
GLRA1 P23415 1/20 0.43
PTPN1 P18031 1/20 0.43
CYP1A2 P05177 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
CYP2C19 P33261 1/20 0.43
PTGS2 P35354 1/20 0.43
SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535983 0.88 LMNA (0.53) MRGPRX4THRBMAPTGAALMNA
SCHEMBL8405763 0.88 LMNA (0.50) MRGPRX4KDM4ETHRBMAPTTP53
SCHEMBL8408594 0.84 MRGPRX4 (0.47) MRGPRX4KDM4EMAPTTP53MEN1
SCHEMBL1207327 0.83 ALDH1A1 (0.56) MRGPRX4KDM4ETHRBMAPTTP53
SCHEMBL29955265 0.82 MRGPRX4 (0.51) MRGPRX4KDM4ETHRBMAPTTP53
SCHEMBL16351377 0.82 MRGPRX4 (0.68) MRGPRX4KDM4ETP53LMNAHPGD
SCHEMBL8408574 0.81 LMNA (0.61) MAPTTP53GAALMNAMEN1
SCHEMBL257799 0.80 MAPK1 (0.51) MRGPRX4KDM4ETHRBMAPTTP53
SCHEMBL7637040 0.79 LMNA (0.49) MRGPRX4GAALMNAHPGDMEN1
SCHEMBL8405859 0.79 GSTP1 (0.46) KDM4ETHRBMAPTTP53GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1217933-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2005-09-07 CN disclosed
CN-1654455-A Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2005-08-17 CN disclosed
CN-1128777-C Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2003-11-26 CN disclosed
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
CN-1088061-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2002-07-24 CN disclosed
US-6376428-B1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-23 US disclosed
CN-1318535-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2001-10-24 CN disclosed
US-6268313-B1 CONTROLLING INSECTS, MITES, TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-31 US disclosed
US-6071861-A FOR THE CONTROL OF NOXIOUS INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, INC. (JP) 2000-06-06 US disclosed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
CN-1169147-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1997-12-31 CN disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
CN-1137265-A Dihalopropene compounds, insecticides/acaricides containing the same and intermediates for their production SUMITOMO CHEMICAL CO (JP) 1996-12-04 CN disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC MRGPRX4 1668/4885KDM4E 2102/4885THRB 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.