SCHEMBL7075875

SCHEMBL7075875

NC(=O)N(SC1CCCCC1)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.41
EPHX1 P07099 9/20 0.37
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
MAPT P10636 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
EPHX2 P34913 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7075868 0.90 ALOX5 (0.37) ALOX5EPHX1CES2CES1KMT2A
SCHEMBL3073660 0.88 ALOX5 (0.36) ALOX5EPHX1KMT2A
SCHEMBL18966016 0.77 ALOX5 (0.37) ALOX5EPHX1CES2CES1ALDH1A1
SCHEMBL3075878 0.75 MGLL (0.35) ALOX5CES2CES1
SCHEMBL6832484 0.74 EPHX1 (0.34) ALOX5EPHX1CES2CES1
SCHEMBL3073554 0.72
SCHEMBL3081858 0.70 EPHX1 (0.35) ALOX5EPHX1
SCHEMBL11784109 0.69 EPHX1 (0.41) ALOX5EPHX1CES2CES1NPC1
SCHEMBL20623601 0.69 EPHX1 (0.41) ALOX5EPHX1CES2CES1NPC1
SCHEMBL3070921 0.64 FDPS (0.38) RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed