Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.35 |
| ▸ | PNMT | P11086 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224235 | 0.83 | HRH4 (0.49) | HRH4TRPV4PNMTALDH1A1KDM4E | |
| SCHEMBL22471039 | 0.78 | MAPT (0.35) | ALDH1A1KDM4EGAAKIF11 | |
| SCHEMBL7076049 | 0.76 | ALDH1A1 (0.56) | HRH4TRPV4ALDH1A1KDM4EKIF11 | |
| SCHEMBL2369343 | 0.73 | MKNK2 (0.39) | HRH4TRPV4PNMTALDH1A1KDM4E | |
| SCHEMBL29559790 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAAR | |
| SCHEMBL220780 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAAR | |
| SCHEMBL4911777 | 0.72 | KIF11 (0.46) | HRH4ALDH1A1KDM4EKIF11TRPA1 | |
| SCHEMBL16336032 | 0.71 | MKNK2 (0.40) | HRH4TRPV4ALDH1A1ARPTGDR2 | |
| SCHEMBL7511048 | 0.71 | NCEH1 (0.36) | TRPV4MRGPRX4PTGDR2 | |
| SCHEMBL9231619 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051123-A1 | ISOTHIAZOLYLAMINOCARBONYL DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-06-26 | — | — | WO | disclosed |