Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16346074 | 0.81 | GSTP1 (0.66) | GSTP1MRGPRX4MAOBHDAC4NAAA | |
| SCHEMBL7084289 | 0.79 | MAOB (0.42) | MAOB | |
| SCHEMBL7817624 | 0.79 | GSTP1 (0.60) | GSTP1MRGPRX4MAOBHDAC4NR4A2 | |
| SCHEMBL7989601 | 0.78 | CYP3A4 (0.38) | GSTP1MAOBENPP3ENPP1NR4A2 | |
| SCHEMBL3165173 | 0.78 | CYP4F2 (0.52) | MAOB | |
| SCHEMBL17299381 | 0.77 | LTA4H (0.50) | MAOB | |
| SCHEMBL2137838 | 0.76 | MRGPRX4 (0.69) | GSTP1MRGPRX4MAOBHDAC4NAAA | |
| SCHEMBL9405631 | 0.76 | MAOB (0.71) | GSTP1MRGPRX4MAOBNR4A2 | |
| SCHEMBL25219606 | 0.75 | MAOB (0.41) | MAOB | |
| SCHEMBL31052352 | 0.75 | MAOB (0.41) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |