Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16345874 | 0.84 | GSTP1 (0.48) | CYP3A4MGAMGAASIMGAM2 | |
| SCHEMBL7076110 | 0.78 | GSTP1 (0.46) | MAOBGSTP1ENPP3ENPP1NR4A2 | |
| SCHEMBL8013638 | 0.77 | LTA4H (0.62) | NPC1RAB9ASMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL7989831 | 0.76 | LTA4H (0.53) | KMT2A | |
| SCHEMBL7084289 | 0.74 | MAOB (0.42) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL17299381 | 0.70 | LTA4H (0.50) | MAOBMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL5686505 | 0.69 | PREP (0.38) | CA12CA1CA9 | |
| SCHEMBL22382337 | 0.67 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2MEN1POLB | |
| SCHEMBL31208311 | 0.67 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2MEN1POLB | |
| SCHEMBL970429 | 0.67 | ALDH1A1 (0.35) | CYP3A4CA1CA2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |