Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 12/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 10/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550344 | 0.82 | DDB1 (0.40) | DDB1CRBNCA1CA2CA7 | |
| SCHEMBL29350375 | 0.76 | POLB (0.43) | CA2CA9MEN1KMT2ACYP1A2 | |
| SCHEMBL1414506 | 0.76 | POLB (0.43) | CA2CA9MEN1KMT2ACYP1A2 | |
| SCHEMBL7079743 | 0.75 | S100A4 (0.54) | DDB1CRBNCA1CA2CA7 | |
| Formaldehyde SCHEMBL28703568 | 0.75 | HDAC4 (0.37) | CA2CA9HDAC4HDAC8HDAC6 | |
| SCHEMBL9279014 | 0.73 | DDB1 (0.44) | DDB1CRBNCA1CA2CA7 | |
| SCHEMBL30725964 | 0.72 | MEN1 (0.53) | DDB1CRBNCA1CA2CA7 | |
| SCHEMBL9853616 | 0.72 | ERCC1 (0.52) | DDB1CRBNCA1CA2CA7 | |
| SCHEMBL7568712 | 0.72 | DDB1 (0.43) | DDB1CRBNCA1CA2CA7 | |
| SCHEMBL8418554 | 0.72 | MEN1 (0.53) | DDB1CRBNCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898562-B1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | UPJOHN CO (US) | 2003-01-22 | — | — | EP | claimed |