SCHEMBL9853616

SCHEMBL9853616

O=C1c2cccc(F)c2C(=O)N1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 2/20 0.52
FEN1 P39748 2/20 0.52
ERCC4 Q92889 2/20 0.52
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
POLB P06746 2/20 0.43
MAPT P10636 2/20 0.43
CYP1A2 P05177 1/20 0.43
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PABPC1 P11940 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30643813 0.78 MAOA (0.54) ERCC1FEN1ERCC4CA1CA2
SCHEMBL43760 0.78 PABPC1 (0.55) ERCC1FEN1ERCC4POLBMAPT
SCHEMBL9279014 0.78 DDB1 (0.44) CA1CA2CA7CA9DDB1
SCHEMBL3211320 0.78 MAOA (0.54) ERCC1FEN1ERCC4CA1CA2
SCHEMBL4407778 0.76 MAPT (0.56) ERCC1FEN1ERCC4POLBMAPT
SCHEMBL6656873 0.76 FEN1 (0.52) ERCC1FEN1ERCC4CA1CA2
SCHEMBL9853619 0.76 ERCC1 (0.38) ERCC1FEN1ERCC4POLBMAPT
SCHEMBL3220477 0.76 ERCC1 (0.52) ERCC1FEN1ERCC4CA1CA2
SCHEMBL31405120 0.76 MAPT (0.56) ERCC1FEN1ERCC4POLBMAPT
SCHEMBL30725964 0.76 MEN1 (0.53) CA1CA2CA7CA9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417445-A1 Single pot process for making a fluoroanthranilic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-20 EP claimed
US-4954639-A REACTING FLUOROPHTHALIC ACID COMPOUND WITH HYDROXYLAMINE OR SALT OCCIDENTAL CHEMICAL CORPORATION (US) 1990-09-04 US claimed
US-20230142883-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-11 US disclosed
US-11560381-B1 Compounds and uses thereof FOGHORN THERAPEUTICS INC. (US) 2023-01-24 US disclosed
EP-0417445-A1 Single pot process for making a fluoroanthranilic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-20 EP disclosed
EP-0417445-A1 Single pot process for making a fluoroanthranilic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-20 EP disclosed
US-4954639-A REACTING FLUOROPHTHALIC ACID COMPOUND WITH HYDROXYLAMINE OR SALT OCCIDENTAL CHEMICAL CORPORATION (US) 1990-09-04 US disclosed
US-4954639-A REACTING FLUOROPHTHALIC ACID COMPOUND WITH HYDROXYLAMINE OR SALT OCCIDENTAL CHEMICAL CORPORATION (US) 1990-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142883-A1 COMPOUNDS AND USES THEREOF VHL, TFEB, BECN1 ERCC1 198/4885FEN1 2174/4885ERCC4 90/4885
US-11560381-B1 Compounds and uses thereof VHL, TFEB, BECN1 ERCC1 198/4885FEN1 2174/4885ERCC4 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.