SCHEMBL8418554

SCHEMBL8418554

CN1C(=O)c2cccc(F)c2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
USP2 O75604 3/20 0.53
CASP1 P29466 2/20 0.53
BRCA1 P38398 1/20 0.53
CASP7 P55210 1/20 0.53
CASP3 P42574 1/20 0.48
HPGD P15428 4/20 0.47
MAPT P10636 2/20 0.47
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
POLB P06746 2/20 0.44
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 4/20 0.43
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
ATM Q13315 1/20 0.43
GAA P10253 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30725964 1.00 MEN1 (0.53) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL27322335 0.78 CASP3 (0.38) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL9279014 0.78 DDB1 (0.44) MEN1KMT2ADDB1CRBNATM
SCHEMBL13239551 0.78 MEN1 (0.54) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL2036747 0.78 MEN1 (0.58) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL3218263 0.76 ANPEP (0.54) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL1500604 0.76 ALDH1A1 (0.56) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL30725967 0.76 MEN1 (0.53) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL30788074 0.76 ANPEP (0.54) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL133067 0.76 MEN1 (0.53) MEN1KMT2AUSP2CASP1BRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN disclosed
WO-2022133551-A1 HISTONE DEACETYLASE INHIBITORS THE UNIVERSITY OF QUEENSLAND (AU) 2022-06-30 WO disclosed
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 US disclosed
EP-3658551-B1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROT LTD (GB) 2022-01-19 EP disclosed
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-17 US disclosed
CN-108117645-B Method for preparing polyaryl imide and production device thereof 北京鼎益新材科技有限公司 2020-08-14 CN disclosed
EP-3279193-B1 COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-08 EP disclosed
WO-2019020987-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROTECTION LTD. (GB) 2019-01-31 WO disclosed
WO-2018024723-A1 PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-08 WO disclosed
EP-3279193-A1 COMPOUNDS COMPRISING PHTHALIMIDE AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-07 EP disclosed
US-4960903-A Aromatic compounds having sulfonyl groups TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1990-10-02 US disclosed
EP-0233409-B1 AROMATIC SULFONYL COMPOUNDS Tonen Corporation (JP) 1990-09-26 EP disclosed
EP-0233409-A2 Aromatic sulfonyl compounds Tonen Corporation (JP) 1987-08-26 EP disclosed
US-4476309-A Method for making aromatic etherimides GENERAL ELECTRIC COMPANY (US) 1984-10-09 US disclosed
EP-0119576-A1 Method for making aromatic etherimides GENERAL ELECTRIC COMPANY (US) 1984-09-26 EP disclosed
US-4471125-A Method for making aromatic ether imides GENERAL ELECTRIC COMPANY (US) 1984-09-11 US disclosed
US-4302616-A Method for making alkali metal bisphenoxide salts and bisimides derived therefrom GENERAL ELECTRIC COMPANY (US) 1981-11-24 US disclosed
US-4273712-A PHASE TRANSFER CATALYSTS GENERAL ELECTRIC COMPANY (US) 1981-06-16 US disclosed
US-4257953-A Method for making bisphenoxide salts and bisimides derived therefrom GENERAL ELECTRIC COMPANY (US) 1981-03-24 US disclosed
US-3992407-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES CHRM1, C1S, DNMT3L MEN1 887/4885KMT2A 1260/4885USP2 3112/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM MEN1 2728/4885KMT2A 4062/4885USP2 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.